Product Details
Catalog Number: MO15143
Applications: WB, IHC, IP
Type: Rat IgG
Dilutions: Immunohistochemistry: 8-25 ug/ml Western Blot: 1 ug/ml Immunoprecipitation: 25 ug/ml
Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Chordin-like 2/CHRDL2, Gln24-Leu426
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein A purified
Format B: liquid
Species Reactivity: Mouse
Entrez: 25884
UniProt: Q6WN34
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$319.00Add to Cart

Chordin-like 2 (CHL2; also known as breast tumor novel factor 1/BNF-1), is a secreted glycoprotein that has significant homology to chordin and acts as a TGF-beta superfamily antagonist. CHL2 is a chordin family member with structural homology to CHL1 (also known as neuralin or ventroptin). Mouse CHL2401 cDNA encodes a 4550 kDa, 426 amino acid (aa) residue precursor protein with a putative 25 aa signal peptide and a 401 aa mature segment. The mature segment contains three 63 aa cysteine-rich von Willebrand type C repeats (CRs) that are conserved among chordin family members in the spacing of 10 cysteine residues. It also contains two potential N-linked glycosylation sites and one putative NLS that lies just proximal to the third CR repeat.

Images
Immunohistochemistry

Chordin-like 2/CHRDL2 was detected in immersion fixed frozen sections of embryonic mouse cartilage (15 d.p.c.) using 25 µg/mL Rat Anti-Mouse Chordin-like 2/CHRDL2 Monoclonal Antibody overnight at 4 °C. Tissue was stained with the Anti-Rat HRP-DAB Cell & Tissue Staining Kit and counterstained with hematoxylin (blue)

Immunohistochemistry

Chordin-like 2/CHRDL2 was detected in immersion fixed frozen sections of embryonic mouse cartilage (15 d.p.c.) using 25 µg/mL Rat Anti-Mouse Chordin-like 2/CHRDL2 Monoclonal Antibody overnight at 4 °C. Tissue was stained with the Anti-Rat HRP-DAB Cell & Tissue Staining Kit and counterstained with hematoxylin (blue)