Detects human LC3A in direct ELISA. Human Microtubule-associated Protein (MAP) Light Chain 3 (LC3) A is a121 amino acid (aa) protein with a predicted molecular weight of 14 kDa. It is a member of the LC3 subfamily of Autophagy-related 8 (Atg8) proteins (1). The LC3 subfamily also includes LC3B andLC3C. LC3 exhibits 100% aa sequence identity with its mouse and rat orthologs, and is orthologous to the yeast autophagy-related protein Atg8. Atg8 family members show structural similarity with Ubiquitin, but lack aa sequence similarity. LC3 was originally described as part is part of a complex that includes heavy and light chains comprising the MAP1 family of microtubule regulatory proteins (3). However, LC3 has gained attention for MAP1-independent functions in autophagy.
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Name Catalog # Size Human LC3A Antibody MO15167 100 ug MAP2 CH23032 100 ul MAP2 GT22102 100 ul MAP2 (Microtubule assoc. protein 2) CH22103 50 ul MAP2 (Microtubule assoc. protein 2) MO22116 100 ul MAP2 (Microtubule assoc. protein 2) MO30000 50 ul Tau CH23018 100 ul Tau MO22191 100 ul Tau MO47000 100 ul Tau (Tau 46) MO18002 100 ul Tau /MAPT+ CH22113 100 ul