Product Details
Catalog Number: MO18005
Applications: IHC
Type: Mouse IgG
Immunogen: Produced by immunizing BALB/c mice with stimulated human leukocytes.
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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400 ul$275.00Add to Cart

CD45 antigen is a protein which is a leucocyte common antigen, a type I transmembrane protein present on all differentiated hematopoietic cells except erythrocytes that assists in the activation of those cells (a form of co-stimulation). It is expressed in lymphomas, B-cell chronic lymphocytic leukemia, hairy cell leukemia, and acute nonlymphocytic leukemia.

Studies have shown that expression of CD 45 is elevated in microglia in AD brain compared with controls.

Image: CD45 staining of paraffin-embedded human tonsil.