Product Details
Catalog Number: MO18005
Applications: IHC
Type: Mouse IgG
Immunogen: Produced by immunizing BALB/c mice with stimulated human leukocytes.
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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400 ul$275.00Add to Cart

CD45 antigen is a protein which is a leucocyte common antigen, a type I transmembrane protein present on all differentiated hematopoietic cells except erythrocytes that assists in the activation of those cells (a form of co-stimulation). It is expressed in lymphomas, B-cell chronic lymphocytic leukemia, hairy cell leukemia, and acute nonlymphocytic leukemia.

Studies have shown that expression of CD 45 is elevated in microglia in AD brain compared with controls.

Images
CD45 staining of paraffin-embedded human tonsil

CD45 staining of paraffin-embedded human tonsil

CD45 staining of paraffin-embedded human tonsil

CD45 staining of paraffin-embedded human tonsil