BRAF V600E Antibody detects the V600E mutant form of BRAF (serine/threonine-protein kinase B-Raf). Studies have shown that mutations on the BRAF gene in which 80% are of the single V600E substitution resulted in increase of cell proliferation and resistance to apoptosis. BRAF V600E is therefore an important immunohistochemical marker for tumor studies.
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