GABAA receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics.
Defects in GABA A Receptor beta 3 (GABRB3) is associated with chronic insomnia and childhood absence epilepsy type 5 (ECA5).
Note: This antibody has been developed by UC Davis under a grant by NIH.