Product Details
Catalog Number: MO50002
Applications: WB, IHC, IF
Type: Mouse IgG
Immunogen: Synthetic peptide amino acids 15-34 (CTQPHHGARAMNDIGDYVGS, extracellular N-terminus) of rat GABA-A-R-Delta.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse, Rat
Entrez: 2563
UniProt: O14764
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$405.00Add to Cart

GABAA receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters.They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics.

The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho.(Genome Res. 16 (1): 55–65). Defects in GABA A R, delta (GABRD) gene are associated Ataxi and Generalized Epilepsy.

This antibody has been developed by UC Davis under a grant by NIH.

Images

GABA A Receptor, delta staining of cultured rat hippocampal neuron surface (S, left) and total protein (T, right) Data courtesy of Suchitra Joshi and Jaideep Kapur, University of Virginia.

GABA A Receptor, delta staining of cultured rat hippocampal neuron surface (S, left) and total protein (T, right) Data courtesy of Suchitra Joshi and Jaideep Kapur, University of Virginia.

GABA A Receptor, delta western blot of cerebellar lysate.

GABA A Receptor, delta western blot of cerebellar lysate.