Product Details
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $349.00 | Add to Cart |
Cav1.3 Ca2+ channel or CACN4 encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Cav1.3 voltage-gated L-type calcium channels (LTCCs) translate sound-induced depolarization into neurotransmitter release in auditory hair cells and control diastolic depolarization. These channels also play a major role in the generation of cardiac pacemaker activity by contributing to diastolic depolarization in SAN pacemaker cells. Genetic knockout or pharmacological inhibition of Cav1.3 reverts this dependency back to HCN and protects these neurons in mouse models of Parkinson’s disease in adult mice. Note: Antibody has been developed by UC Davis under a grant by NIH. |
- Product Reviews
Leave a review for this product and you could be eligible for a $10 Starbucks gift card.
- Product Publications
Product Publications
If you've used this product in a publication, let us know. Email rose@neuromics.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Related Products
Name Catalog # Size Bradykinin Receptor B2 RA14137 100 ul CADM1/SynCAM RA25084 100 ul Calbindin CH22118 100 ul Calbindin MO20016 100 ug Calbindin D MO15097 100 ug Calcineurin A MO15055 100 ug Calreticulin MO22164 100 ul Calretinin CH22116 100 ul Calretinin MO20024 100 ul Calretinin MO22166 100 ul Calretinin (IgG1) MO22165 100 ul CaMKII RA18006 100 ul CaMKII2A GT41019 100 ug Cav1.2 Ca2+ channel MO50006 100 ul Cav3.1 Ca2+ channel MO50008 100 ul MARCKS (Myristoylated Alanine Rich C Kinase Substrate) RA22111 100 ul Neurogranin precursor GT41024 100 ug phospho-Synapsin (Ser9) RA18009 100 ul S100B GT15160 100 ug SHANK1a C-terminus RA19016 100 ug SHANK1a N-Terminus RA19015 100 ug Striatin RA25067 100 ul Synapsin RA18010 100 ul Synaptotagmin 1 MO15099 100 ug VAMP-1 GT15236 100 ug
Images
Cav1.3 Ca2+ channel staining of adult rat hippocampus.
Cav1.3 Ca2+ channel staining of adult rat hippocampus.
Cav1.3Ca2+ channel western blots of adult rat brain membrane.
Cav1.3Ca2+ channel western blots of adult rat brain membrane.