Product Details
Catalog Number: MO50008
Applications: ICC, WB, IHC
Type: Mouse IgG
Immunogen: Fusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession number Q9WUT2).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 8913
UniProt: O43497
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$349.00Add to Cart

CaV3.1 Ca2+ channel (also known as Voltage-gated/dependent T-type calcium channel alpha-1-G subunit, CACNA1g and NBR13) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. CAV3.1 is present primarily in neurons (brain and spinal cord) and cardiac tissue.

In the heart, CAV3.1  may be involved in pacemaker current. It also inhibits thalamic sensory transmission to promote sleep. CAV3.1 could play a role in pain processing and neuro-disorders such as epilepsy.

Note: This antibody has been developed by UC Davis under a grant by NIH.

Images
Cav3.1 Ca2+ channel staining Bottom left: mouse (A) thalamus and (B)cortex (left) and (C) molecular layer of cerebellum (right). Courtesy of Laxmi Parajuli and Ryuichi Shigemoto, NIPS.

Cav3.1 Ca2+ channel staining Bottom left: mouse (A) thalamus and (B)cortex (left) and (C) molecular layer of cerebellum (right). Courtesy of Laxmi Parajuli and Ryuichi Shigemoto, NIPS.

Cav3.1 Ca2+ channel staining Bottom left: mouse (A) thalamus and (B)cortex (left) and (C) molecular layer of cerebellum (right). Courtesy of Laxmi Parajuli and Ryuichi Shigemoto, NIPS.

Cav3.1 Ca2+ channel staining Bottom left: mouse (A) thalamus and (B)cortex (left) and (C) molecular layer of cerebellum (right). Courtesy of Laxmi Parajuli and Ryuichi Shigemoto, NIPS.

Cav3.1 Ca2+ channel western blots of adult rat brain membrane.

Cav3.1 Ca2+ channel western blots of adult rat brain membrane.

Cav3.1 Ca2+ channel western blots of adult rat brain membrane.

Cav3.1 Ca2+ channel western blots of adult rat brain membrane.