CaV3.1 Ca2+ channel (also known as Voltage-gated/dependent T-type calcium channel alpha-1-G subunit, CACNA1g and NBR13) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. CAV3.1 is present primarily in neurons (brain and spinal cord) and cardiac tissue.
In the heart, CAV3.1 may be involved in pacemaker current. It also inhibits thalamic sensory transmission to promote sleep. CAV3.1 could play a role in pain processing and neuro-disorders such as epilepsy.
Note: This antibody has been developed by UC Davis under a grant by NIH.
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