Product Details
Catalog Number: MO50009
Applications: WB, IHC, IP
Type: Mouse IgG
Immunogen: Synthetic peptide amino acids 930-947 (FKSEKVVVEDTVPIIPKE) of rat TrpC4 (also known as short transient receptor potential channel 4, Trp4, capacitative calcium entry channel 1 and CCE1, accession number O35119).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Supernatant
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 7223
UniProt: Q9UBN4
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$349.00Add to Cart

TRPC4 (Transient receptor potential cation channel, subfamily C, member 5)  is one of 7 mammalian TRPC proteins. It forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation including angiogenesis.

 TRPC4 could contribute to late onset Alzheimer's and certain Cardiovascular Diseases.

Note: This antibody has been developed by UC Davis under a grant by NIH.

Images

TRPC4 staining of adult rat hippocampus.

TRPC4 staining of adult rat hippocampus.

TRPC4 western blots of extracts of adult rat brain membrane (RBM) and COS cells transiently transfected with TrpC4.

TRPC4 western blots of extracts of adult rat brain membrane (RBM) and COS cells transiently transfected with TrpC4.