TRPC5 (Transient receptor potential cation channel, subfamily C, member 5) is one of 7 mammalian TRPC proteins. It functions as an innocuous cold transducer in nociceptive and thermosensory nerve endings. It plays a role in the activiating the channel for semaphorin 3A-induced neuronal growth cone collapse
TRPC5 mediated Rho GTPase signaling may cause podocyte damage, and TRPC channels may therefore provide a novel target for anti-proteinuric therapies in acquired, Angiotensin-associated proteinuric disease such as hypertensive and/or diabetic nephropathy.
Note: This antibody has been developed by UC Davis under a grant by NIH.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size Trp-p8 RA19043 100 ul TRPA1 RA14135 100 ul TRPA1 RA25013 100 ul TRPC4 MO50009 100 ug TRPC7 GT41031 100 ug TRPM2 RA25034 100 ul TRPM6 (Chak2) GP14108 100 ul TRPM7 GT41030 100 ug VR1 C-terminus (TRPV1) GP14100 150 ul VR1 C-terminus (TRPV1) GP14100 50 ul VR1 N-Terminus (TRPV1) RA10110 150 ul VR1 N-Terminus (TRPV1) RA10110 50 ul