Four KChIP proteins constitute the fifth subfamily (Class E) and are unique to mammals. KChIPs interact with voltage-gated potassium channels and presenilins [5-8]. KChIP1, KChIP3, KChIP4 are expressed predominantly in brain, while KChIP2 is highly expressed in both heart and brain.
K+ channel interacting protein 1 (KChIP1) is a neuronal calcium sensor (NCS) protein that interacts with multiple intracellular molecules. It regulates behavioral anxiety by modulating inhibitory synaptic transmission, and drugs that act on KChIP1 may help to treat patients with mood disorders including anxiety.
Note: Antibody has been developed by UC Davis under a grant by NIH.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size ATPase Na+/K+ transporting alpha 1 MO25023 50 ul KChIP2b K+ channel MO50012 100 ul Kir2.1 K+ channel MO50013 100 ul Kir2.2 K+ channel MO50014 100 ul Kv1.1 K+ channel MO50015 100 ul Kv1.2 K+ channel MO50016 100 ul Kv1.3 K+ channel MO50017 100 ul Kv1.4 K+ channel MO50018 100 ul Kv2.1 K+ channel MO50019 100 ul Kv3.1 K+ channel (pSer503) RA25020 100 ul Kv3.1b K+ channel MO50020 100 ul Kv4.2 K+ channel MO50021 100 ul Kv7.1/KCNQ1 K+ channel MO50022 100 ul TREK 1 RA25018 100 ul