Product Details
Catalog Number: MO50013
Applications: ICC, WB
Type: Mouse IgG
Immunogen: Synthetic peptide amino acids 390-411 (cytoplasmic C-terminus) of mouse Kir2.1 (accession number P35561).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse, Rat
Entrez: 3759
UniProt: P63252
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$405.00Add to Cart

Kir K+, KCNJ2 or Inwardly rectifying potassium channels pass current (positive charge) more easily in the inward direction (into the cell). It is thought that this current may play an important role in regulating neuronal activity, by helping to establish the resting membrane potential of the cell.

Defects this channel are the cause of long QT syndrome type 7 and short QT syndrome type 3. They are characterized by ECG arrythmias and cause syncope and sudden death in response to excercise or emotional stress.

Note: Antibody has been developed by UC Davis under a grant by NIH.

Images
Kir2.1 staining of adult rat hippocampus.

Kir2.1 staining of adult rat hippocampus.

Kir2.1 staining of adult rat hippocampus.

Kir2.1 staining of adult rat hippocampus.

Kir2.1 K+ Channel western blots of Rat Brain Membranes (RBM) and COS cells transiently transfected with HA-tagged Kir2.1 or untagged Kv2.1 plasmids.

Kir2.1 K+ Channel western blots of Rat Brain Membranes (RBM) and COS cells transiently transfected with HA-tagged Kir2.1 or untagged Kv2.1 plasmids.

Kir2.1 K+ Channel western blots of Rat Brain Membranes (RBM) and COS cells transiently transfected with HA-tagged Kir2.1 or untagged Kv2.1 plasmids.

Kir2.1 K+ Channel western blots of Rat Brain Membranes (RBM) and COS cells transiently transfected with HA-tagged Kir2.1 or untagged Kv2.1 plasmids.