Catalog Number: MO50014
Applications: ICC, WB
Type: Mouse IgG
Immunogen: Synthetic peptide amino acids 390-410 of rat Kir2.2
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Rat
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Kir2.2 participates in establishing action potential waveform and excitability of neuronal and muscle tissues. This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of the multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17.
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