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Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 1 Hippocampal pair | $275.00 | Add to Cart |
Primary Rat Hippocampal Cells are live neurons isolated from micro surgically dissected regions of day 18 embryonic Sprague/Dawley rat brain. These cells are prepared fresh each week and shipped in a nutrient rich medium that keeps the cells alive for up to 7 days under refrigeration. For long term culture protocol (120 days) see: Todd GK, Boosalis CA, Burzycki AA, Steinman MQ, Hester LD, Shuster PW, et al. (2013) Towards Neuronal Organoids: A Method for Long-Term Culturing of High-Density Hippocampal Neurons. PLoS ONE 8(4): e58996. https://doi.org/10.1371/journal.pone.0058996 |
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- Product Publications
Product Publications
- Farina J. Mahmud, Thomas Boucher, Shijun Liang, and Amanda M. Brown. (2020). Osteopontin and Integrin Mediated Modulation of Post-Synapses in HIV Envelope Glycoprotein Exposed Hippocampal Neurons. Brain Sciences, 10(6), 346. doi: 10.3390/brainsci10060346
- Chiara Porro, Antonia Cianciulli, Teresa Trotta, Dario Domenico Lofrumento, Rosa Calvello and Maria Antonietta Panaro. (2019). Formyl-methionyl-leucyl-phenylalanine Induces Apoptosis in Murine Neurons: Evidence for NO-Dependent Caspase-9 Activation. Biology 8(1), 4; doi:10.3390/biology8010004
- Swarup Vimal & Balagurunathan Kuberan.(2018) Click-xylosides overcome neurotoxic effects of reactive astrocytes and promote neuronal growth in a cell culture model of brain injury. bioRxiv doi: http://dx.doi.org/10.1101/286450.
- Mahendran Subramanian, Aimee‐Jayne Tyler, Eva Maria Luther, Elena Di Daniel, Jenson Lim and Jon Dobson. (2017). Oscillating Magnet Array−Based Nanomagnetic Gene Transfection: A Valuable Tool for Molecular Neurobiology Studies. Nanomaterials 7, 28; doi: 10.3390/nano7020028
- Scott E. Counts and Elliott J. Mufson. (2010). Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity. Journal of Neurochemistry. Journal of Neurochemistry, Volume 113 Issue 3, Pages 649 - 660. doi: 10.1111/j.1471-4159.2010.06622.x
- Karunya K. Kandimalla1, Olenych G. Scott, Smita Fulzele1, Michael W. Davidson, Joseph F. Poduslo. (2009). Mechanism of Neuronal versus Endothelial Cell Uptake of Alzheimer's Disease Amyloid β Protein. PLoS ONE 4(2): e4627. doi:10.1371/journal.pone.0004627
- Jennifer M Laing and Laure Aurelian. (2008). ΔRR vaccination protects from KA-induced seizures and neuronal loss through ICP 10PK-mediated modulation of the neuronal-microglial axis. Genetic Vaccines and Therapy, doi: 10.1186/1479-0556-6-1
- Brian Hoffpauir , Emily McMains, and Evanna Gleason. (2006). Nitric Oxide Transiently Converts Synaptic Inhibition to Excitation in Retinal Amacrine Cells J Neurophysiol, 95: 2866-2877, doi: 10.1152/jn.01317.2005
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Images
(A) F-Aβ40 uptake; (B) Uptake of AF633-Trf; (C) Superimposition of images A and B; (D) Overlay of fluorescence images on the DIC image of RPH neurons. (E) Uptake of F-Aβ40; (F) No significant neuronal uptake of AF633-Trf at 4°C; (G) Superimposition of images D and E on the DIC image of RPH neurons; (H) Uptake of F-Aβ40; (I) No significant cellular uptake of AF633-Trf was observed; (J) Superimposition of images H & I on the DIC image of neurons.
(A) F-Aβ40 uptake; (B) Uptake of AF633-Trf; (C) Superimposition of images A and B; (D) Overlay of fluorescence images on the DIC image of RPH neurons. (E) Uptake of F-Aβ40; (F) No significant neuronal uptake of AF633-Trf at 4°C; (G) Superimposition of images D and E on the DIC image of RPH neurons; (H) Uptake of F-Aβ40; (I) No significant cellular uptake of AF633-Trf was observed; (J) Superimposition of images H & I on the DIC image of neurons.
E18 hippocampal neurons stained with Tau (red, CH22113) and Doublecortin (green, MO22113). The two proteins overlap in the proximal dendrites (yellow) Axons (low doublecortin content) are red. Blue staining is the nuclear DNA
E18 hippocampal neurons stained with Tau (red, CH22113) and Doublecortin (green, MO22113). The two proteins overlap in the proximal dendrites (yellow) Axons (low doublecortin content) are red. Blue staining is the nuclear DNA
Embryonic day-18 primary rat hippocampal cells (PC 35101) grown over pLL-coated 6-well plate for 48 hours. Green: anti-rat TAU/MAPT (CH22113), blue: DAPI. Scale bar = 25 um.
Embryonic day-18 primary rat hippocampal cells (PC 35101) grown over pLL-coated 6-well plate for 48 hours. Green: anti-rat TAU/MAPT (CH22113), blue: DAPI. Scale bar = 25 um.