Product Details
Catalog Number: PR15101CF
Type: Protein
Storage: This product can be stored for up to 1 month at 2°C to 8°C under sterile condition after opening, for up to 3 months at -20°C to -70°C under sterile condition after opening, or for up to 12 months at -20°C to -70°C as supplied. Avoid freeze-thaw cycles.
Shipping: Shipped on Dry Ice
Format A: liquid
Species Reactivity: Human
Entrez: 10533
UniProt: O95352
Downloads: Datasheet (pdf)
Product Sizes
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50 ug$409.00Add to Cart

ATG7, also known as APG7, is a 78 kDa cytosolic ubiquitin­E1-­like enzyme that plays a key role in the autophagy pathway of intracellular bulk degradation. It is required for the conjugation of ATG5 to ATG12, the lipidation of ATG8 proteins including GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A, and the subsequent formation of autophagosomes. ATG7 is required for mitochondrial removal during erythropoiesis (“mitophagy”) and for the maintenance of axonal homeostasis.

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