Product Details
Catalog Number: PR15122CF
Type: Protein
Storage: This product can be stored for up to 1 month at 2°C to 8°C under sterile condition after reconstitution, for up to 3 months at -20°C to -70°C under sterile condition after reconstitution, or for up to 12 months at -20°C to -70°C, as supplied. Avoid freeze-thaw cycles.
Shipping: Ambient
Format B: lyophilized
Species Reactivity: Human, Mouse, Rat
Entrez: 3624
UniProt: P08476
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
10 ug$429.00Add to Cart
50 ug$1,229.00Add to Cart

Activin and Inhibin are members of the TGF-beta superfamily of cytokines and are involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Activin and Inhibin are produced as precursor proteins. Activin A exerts its biological activities by binding to the type 2 serine/threonine kinase Activin RIIA which then noncovalently associates with the type 1 serine/threonine kinase Activin RIB/ALK-4.

Images
Bioactivity

GMP-grade Recombinant Human/Mouse/Rat Activin A induces hemoglobin expression in K562 human chronic myelogenous leukemia cells in a dose-dependent manner. The ED50 for this effect is 0.2‑1.2 ng/mL.

Bioactivity

GMP-grade Recombinant Human/Mouse/Rat Activin A induces hemoglobin expression in K562 human chronic myelogenous leukemia cells in a dose-dependent manner. The ED50 for this effect is 0.2‑1.2 ng/mL.

SDS-PAGE

1 μg/lane of GMP-grade Recombinant Human/Mouse/Rat Activin A was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing single bands at 14 kDa and 24 kDa, respectively.

SDS-PAGE

1 μg/lane of GMP-grade Recombinant Human/Mouse/Rat Activin A was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing single bands at 14 kDa and 24 kDa, respectively.