Product Details
Catalog Number: PR15131CF
Type: Protein
Storage: This product can be stored for up to 1 month at 2°C to 8°C under sterile condition after reconstitution, for up to 3 months at -20°C to -70°C under sterile condition after reconstitution, or for up to 12 months at -20°C to -70°C, as supplied. Avoid freeze-thaw cycles.
Shipping: Ambient
Format B: lyophilized
Species Reactivity: Human
Entrez: 7040
UniProt: P01137
Downloads: Datasheet (pdf)
Product Sizes
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10 ug$1,259.00Add to Cart

TGF-beta 1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure. TGF-beta 1, 2 and 3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition.

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Bioactivity

GMP-grade Recombinant Human TGF-beta 1 inhibits Recombinant Mouse IL‑4 induced proliferation in the HT-2 mouse T cell line. The ED50 for this effect is 0.04-0.2 ng/mL.

Bioactivity

GMP-grade Recombinant Human TGF-beta 1 inhibits Recombinant Mouse IL‑4 induced proliferation in the HT-2 mouse T cell line. The ED50 for this effect is 0.04-0.2 ng/mL.

SDS-PAGE

1 μg/lane of GMP‑grade Recombinant Human TGF-beta 1 was resolved with SDS-PAGE under reducing (R) and nonreducing (NR) conditions and visualized by silver staining, showing single bands at 12 kDa and 24 kDa, respectively.

SDS-PAGE

1 μg/lane of GMP‑grade Recombinant Human TGF-beta 1 was resolved with SDS-PAGE under reducing (R) and nonreducing (NR) conditions and visualized by silver staining, showing single bands at 12 kDa and 24 kDa, respectively.