Product Details
Catalog Number: RA14113
Applications: WB, IHC
Type: Rabbit IgG
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: liquid
Species Reactivity: Mouse
Entrez: 7442
UniProt: Q8NER1
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$395.00Add to Cart
50 ul$225.00Add to Cart

TRPV1 antagonists have shown efficacy in reducing nociception from inflammatory and neuropathic pain models in rats.[11] This provides evidence that TRPV1 is the capsaicin's sole receptor. In humans, drugs acting at TRPV1 receptors could potentially be used to treat neuropathic pain associated with multiple sclerosis, chemotherapy, or amputation, as well as pain associated with the inflammatory response of damaged tissue, such as in osteoarthritis.

 

Supporting Products
NameCatalog #Size
VR1 C-Terminus (TRPV1) - mouse specificP14113100 ug Blocking Peptide
Images

A Confocal image stack through GCL and NFL of peripheral retina shows TRPV1 in retinal ganglion cell (RGC) bodies (bracket) and in small bundles of RGC axons (arrows). doi:10.1167/iovs.08-2321

A Confocal image stack through GCL and NFL of peripheral retina shows TRPV1 in retinal ganglion cell (RGC) bodies (bracket) and in small bundles of RGC axons (arrows). doi:10.1167/iovs.08-2321

VR1 immunoreactivity in mouse dorsal root ganglion. Animals were perfusion fixed with 2% paraformaldehyde. Image courtesy of Dr. Zunyi Wang, University of Wisconsin, Madison.

VR1 immunoreactivity in mouse dorsal root ganglion. Animals were perfusion fixed with 2% paraformaldehyde. Image courtesy of Dr. Zunyi Wang, University of Wisconsin, Madison.