Product Details
Catalog Number: RA15042
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: KLH coupled synthetic peptide CEPEAEAEPEPELE PEPDPEP corresponding to amino acids 176 - 195 of human ARC an inhibitor of apoptosis. Cysteine was added to the amino-terminal for coupling to KLH and for coupling to affinity matrix.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 8996
UniProt: O60936
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

ARC [Apoptosis Repressor with CARD (Caspase-recruitment Domain)] is a 29 kDa cytosolic protein containing an N-terminal CARD joined to a C-terminal region rich in proline and glutamic acid. The expression of human ARC is primarily restricted to skeletal muscle and cardiac tissue. ARC inhibits apoptosis induced by Caspase-8.

Images

ARC Staining in Human Breast Cancer Tissue (a-f). ARC IHC with Antiserum Against Residues 176-195. Courtesy of Isabelle Mercier, Albert Einstein College of Medicine.

ARC Staining in Human Breast Cancer Tissue (a-f). ARC IHC with Antiserum Against Residues 176-195. Courtesy of Isabelle Mercier, Albert Einstein College of Medicine.