Product Details
Catalog Number: RA15046
Applications: ICC, IHC
Type: Rabbit IgG
Immunogen: CRGTELDCGIETD (a.a. 163 - 175 of Caspase-3)
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 836
UniProt: P42574
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
50 ug$255.00Add to Cart

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. They are expressed as latent zymogens and are activated by an autoproteolytic mechanism or by processing by other proteases (frequently other caspases). Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7). Image: Detection of active caspase-3 in paraffin-embedded mouse thymus tissue. sections using rabbit anti-human/mouse active caspase-3 affinity-purified antibody. Tissueswere stained using anti-rabbit HRP-DAB (brown color) Cell and Tissue Staining Kit and counterstained with hematoxylin (blue color).

Images

Immunostaining for activated caspase-3 (red) and proteolipid protein (PLP1) in the cortex of P16 msd/Y mutant mouse. Inset shows DAPI staining for nuclei (top), PLP1 (middle) and activated caspase-3 (bottom). Data Courtesy of Ramaswamy Sharma and Dr. Alexander Gow, Wayne State University.

Immunostaining for activated caspase-3 (red) and proteolipid protein (PLP1) in the cortex of P16 msd/Y mutant mouse. Inset shows DAPI staining for nuclei (top), PLP1 (middle) and activated caspase-3 (bottom). Data Courtesy of Ramaswamy Sharma and Dr. Alexander Gow, Wayne State University.

Detection of active caspase-3 in paraffin-embedded mouse thymus tissue. sections using rabbit anti-human/mouse active caspase-3 affinity-purified antibody. Tissueswere stained using anti-rabbit HRP-DAB (brown color) Cell and Tissue Staining Kit and counterstained with hematoxylin (blue color).

Detection of active caspase-3 in paraffin-embedded mouse thymus tissue. sections using rabbit anti-human/mouse active caspase-3 affinity-purified antibody. Tissueswere stained using anti-rabbit HRP-DAB (brown color) Cell and Tissue Staining Kit and counterstained with hematoxylin (blue color).