Product Details
Catalog Number: RA25044
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: Detects endogenous levels of FOXD3 protein.
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 27022
UniProt: Q9UJU5
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

Embryonic stem cells require the forkhead transcriptional regulator FoxD3 for survival. Following gastrulation, FoxD3 generally gets downregulated, except in the neural crest. A variety of growth factors induce FoxD3 expression, including FGF8 and SNAIL, maintaining the effected cells in an undifferentiated state. Thus defects in FoxD3 induction may cause premature differentiation and/or migration-asociated birth defects.

Images

Western blot analysis of FoxD3 (R233) antibody in extracts from HUVEC cells.

Western blot analysis of FoxD3 (R233) antibody in extracts from HUVEC cells.