Product Details
Catalog Number: RA30026
Applications: IHC, E
Type: Rabbit IgG
Immunogen: KLH Coupled Synthetic Peptide- Amino acids 320 to 335 of human WISP3.
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 8838
UniProt: O95389
Downloads: SDS (pdf)
Downloads: Datasheet (pdf)
Product Sizes
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50 ug$435.00Add to Cart

WISP3 is a member of the CCN (for CTGF, CYR61), and NOV gene family, which encode cysteine-rich secreted proteins with roles in cell growth and differentiation. WISP3 is likely required for normal postnatal skeletal growth and cartilage homeostasis. WISP3 is predominantly expressed in adult and fetal kidney and adult testis

Defects in WISP3 are the cause of progressive pseudorheumatoid arthropathy of childhood. This progressive disease is a primary disorder of articular cartilage with continued cartilage loss and destructive bone changes with aging.

Images

WISP-3 staining of Human Small Intestine. Formalin-Fixed Paraffin-Embedded (FFPE).

WISP-3 staining of Human Small Intestine. Formalin-Fixed Paraffin-Embedded (FFPE).