Product Details
Catalog Number: GT15078
Applications: WB, IHC, E
Type: Goat IgG
Dilutions: IHC 5-15ug/mL; WB 1-2 ug/mL; E 0.5 -1.0 ug/mL
Immunogen: Recombinant human ADAM10, a.a. 214 - 672
Storage: Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE.

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Images

ADAM10 staining of paraffin-embedded human prostate cancer tissue. Tissues were stained Goat HRP-DAB (red-brown) and counterstained with hematoxylin (blue).

ADAM10 staining of paraffin-embedded human prostate cancer tissue. Tissues were stained Goat HRP-DAB (red-brown) and counterstained with hematoxylin (blue).