Product Details
Catalog Number: GT15093
Applications: ICC, WB, IHC, E
Type: Goat IgG
Immunogen: NS0-derived, recombinant mouse Fibroblast Growth Factor Receptor 5 beta (rmFGF R5?).
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse, Rat
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing.

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