Product Details
Catalog Number: GT15094
Applications: ICC, WB, E
Type: Goat IgG
Dilutions: E. coli-derived rhSOX17 (aa 177 - 414)
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 64321
UniProt: Q9H6I2
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate.

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development.

Images

SOX17 protein is present in various maturation stages of spermatogenesis: spermatogonium (black arrow), secondary spermatocyte (white arrow), and spermatid (black arrowhead), while primary spermatocytes, spermatozoa, and Sertoli cells are negative. 10.1002/path.2332. Copyright © 2008 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

SOX17 protein is present in various maturation stages of spermatogenesis: spermatogonium (black arrow), secondary spermatocyte (white arrow), and spermatid (black arrowhead), while primary spermatocytes, spermatozoa, and Sertoli cells are negative. 10.1002/path.2332. Copyright © 2008 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

SOX17 staining of endodermal cells derived from human embyronic stem cells. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody and counterstained using Fluoro Nissl (green). Courtesy of Dr. Jong-Hoon Kim and Dr. Ron McKay from the National Institute of Neurological Disorders and Stroke & Stem Cell Unit at NIH.

SOX17 staining of endodermal cells derived from human embyronic stem cells. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody and counterstained using Fluoro Nissl (green). Courtesy of Dr. Jong-Hoon Kim and Dr. Ron McKay from the National Institute of Neurological Disorders and Stroke & Stem Cell Unit at NIH.