Product Details
Catalog Number: GT15097
Applications: WB, IHC, E, IP
Type: Goat IgG
Immunogen: Recombinant human Kallikrein 6
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

Kallikrein 6, also known as Zyme, Neurosin, PRSS9, myelencephalon-specific protease (MSP) and protease M, is a trypsin-like serine proteinase. Kallikrein 6 was originally described from the brain as an enzyme involved in degradation of amyloid plaque protein (APP) and hK6 was thought to be a beta secretase. Kallikrein 6 was shown to be elevated in the sera patients with Alzheimer’s disease and Parkinson’s disease and in animal models of multiple sclerosis.

 Kallikrein 6 is found in greatest abundance in the brain, neuronal tissues and human breast milk with lesser levels in the kidney, thymus, spleen and lymph nodes.

Images
Kallikrein 6 satining paraffin embedded of breast cancer tissue sections Tissues were stained using anti-goat HRPDAB (brown) and counter-stained with hematoxylin (blue).

Kallikrein 6 satining paraffin embedded of breast cancer tissue sections Tissues were stained using anti-goat HRPDAB (brown) and counter-stained with hematoxylin (blue).

Kallikrein 6 satining paraffin embedded of breast cancer tissue sections Tissues were stained using anti-goat HRPDAB (brown) and counter-stained with hematoxylin (blue).

Kallikrein 6 satining paraffin embedded of breast cancer tissue sections Tissues were stained using anti-goat HRPDAB (brown) and counter-stained with hematoxylin (blue).