Kallikrein 6, also known as Zyme, Neurosin, PRSS9, myelencephalon-specific protease (MSP) and protease M, is a trypsin-like serine proteinase. Kallikrein 6 was originally described from the brain as an enzyme involved in degradation of amyloid plaque protein (APP) and hK6 was thought to be a beta secretase. Kallikrein 6 was shown to be elevated in the sera patients with Alzheimer’s disease and Parkinson’s disease and in animal models of multiple sclerosis.
Kallikrein 6 is found in greatest abundance in the brain, neuronal tissues and human breast milk with lesser levels in the kidney, thymus, spleen and lymph nodes.
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Name Catalog # Kallikrein 11 GT15082 Kallikrein 10 GT15096 Kallikrein 5/KLK5/KLKL2 MO15028 Kallikrein 11 MO15030 Kallikrein 8/KLK8/Neuropsin MO15032 Aurora A kinase MO22137 Aurora B kinase MO22138 Aurora A/B/C kinase MO22139 KLK-3 (PSA) RA19044 KLK-L1 RA19045 Kallikrein 5/KLK5/KLKL2 RA19046 KLK-L3 (KLK9) RA19047 KLK-L4 RA19048 KLK12 RA19049 KLK14 RA19050 KLK15 RA19051