The Interleukin 1 receptor family (IL-1 R) comprises at least nine members including IL-1 R1, IL-1 R2 (IL-1 RII), IL-1 R3 (IL-1 RAcP), IL-1 R4 (ST2/T1), IL-1 R5 (IL-18 R alpha/IL-1 Rrp), IL-1 R6 (IL-1 Rrp2/IL-1 RL2), IL-1 R7 (AcPL/IL-18 Rb), IL-1 R8 (TIGIRR-2) and IL-1 R9 (TIGIRR-1). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) which differs from the other nine members by having only one Ig domain, has also been identified. See IL-18 R alpha for IL-1 R5 and IL-18 R beta for IL-1 R7.
- Product Reviews
- Related Products
Name Catalog # Fractalkine(CX3CL1) GT15024 Macrophage Inflammatory Protein 1alpha (MIP-1a)/CCL3 GT15070 Macrophage Inflammatory Protein 1beta (MIP-1beta)/CCL4 GT15071 IL-1 alpha/IL-F1 GT15101 IL-6 (Mouse) GT15103 IL-1 beta (Rat) GT15105 IL-6 (Rat) GT15106 TNF alpha GT15113 IL-2 (Rat) GT15155 CXCL8/IL-8 GT15156 IL-2 MO15069 IL-4 MO15071 IL-17 MO15110 IL-17E/IL-25 MO15111