Product Details
Catalog Number: GT15129
Applications: WB, IHC
Type: Goat IgG
Immunogen: KLH-coupled synthetic peptide corresponding to amino acid residues 4 - 21 of Vanilloid Receptor 1
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse, Rat
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

VR1, also known as TRPV1 (Transient Receptor Potential Vanilloid 1) and capsaicin receptor, is a 115 kDa integral membrane ion channel that has six transmembrane domains and contains intracellular N-and C-termini. It contributes to normal pain and temperature sensation and also has a "sensory-effector" function. By alternative splicing, at least three VR1 isoforms are known. The sequence of residues 4 - 21 of rat VR1 is 78% and 28% identical to that of mouse and human VR1, respectively.

Images
VR1 staining in Rat DRG: red color - TRPV1 labeling, green-counterstain.

VR1 staining in Rat DRG: red color - TRPV1 labeling, green-counterstain.

VR1 staining in Rat DRG: red color - TRPV1 labeling, green-counterstain.

VR1 staining in Rat DRG: red color - TRPV1 labeling, green-counterstain.