Product Details
Catalog Number: GT15146
Applications: WB, E
Type: Goat IgG
Immunogen: NS0-derived, recombinant rat muscle-specific kinase (rrMuSK) extracellular domain.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Rat
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

Receptor Tyrosine Kinases (RTKs) are widely expressed transmembrane proteins that act as receptors for growth factors, neurotrophic factors, and other extracellular signaling molecules. Upon ligand binding, they undergo tyrosine phosphorylation at specific residues in the cytoplasmic tail. This leads to the binding of protein substrates and/or the establishment docking sites for adaptor proteins involved in RTK-mediated signal transduction. RTKs have critical functions in several developmental processes including regulating cell survival, proliferation, and motility. When unregulated, they play prominent roles in cancer formation.

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