Product Details
Catalog Number: GT15148
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: NS0-derived, recombinant human Tie 2 (rhTie 2) extracellular domain.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 7010
UniProt: Q02763
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

Tie-1/Tie (tyrosine kinase with Ig and EGF homology domains 1) and Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains, followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.

Images
Tie-2 Staining in Paraffin-embedded tissue sections of human placenta (cross-section through the blood vessel) were stained with anti-goat HRP-AEC (red) and Haematoxylin (blue) counterstain.

Tie-2 Staining in Paraffin-embedded tissue sections of human placenta (cross-section through the blood vessel) were stained with anti-goat HRP-AEC (red) and Haematoxylin (blue) counterstain.

Tie-2 Staining in Paraffin-embedded tissue sections of human placenta (cross-section through the blood vessel) were stained with anti-goat HRP-AEC (red) and Haematoxylin (blue) counterstain.

Tie-2 Staining in Paraffin-embedded tissue sections of human placenta (cross-section through the blood vessel) were stained with anti-goat HRP-AEC (red) and Haematoxylin (blue) counterstain.