Product Details
Catalog Number: GT15149
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: Insect cell line Sf 21-derived, recombinant human Activin RIIA (rhActivin RIIA) extracellular domain.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins have a wide range of biological activities including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis, and reproductive physiology. Activins are also involved in growth and differentiation of several tissues from different species.

Type II receptors are considered to be constitutively active kinases. Activin has been suggested to be an autocrine/paracrine regulator in the human placenta. The presence of ACVR2 mRNA has been demonstrated in human trophoblast cells and there is also evidence of expression of the gene in human brain and ovary.

Images
staining of Activin RIIA in human prostate cancer. Cells were stained with ABC-HRP + AEC (red) and Haematoxylin (blue) counterstain.

Staining of Activin RIIA in human prostate cancer. Cells were stained with ABC-HRP + AEC (red) and Haematoxylin (blue) counterstain.

staining of Activin RIIA in human prostate cancer. Cells were stained with ABC-HRP + AEC (red) and Haematoxylin (blue) counterstain.

Staining of Activin RIIA in human prostate cancer. Cells were stained with ABC-HRP + AEC (red) and Haematoxylin (blue) counterstain.