Product Details
Catalog Number: GT15158
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: Purified, NSO derived, recombinant human insulin like growth factor binding protein-4 (rhlGFBP-4).
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.

Images
IGFBP-4 stainning of Paraffin-embedded tissue sections of human placenta (chorionic villi). Tissue was stained with  HRP-AEC Cell and Tissue Staining Kit (red) and Haematoxylin (blue).

IGFBP-4 stainning of Paraffin-embedded tissue sections of human placenta (chorionic villi). Tissue was stained with HRP-AEC Cell and Tissue Staining Kit (red) and Haematoxylin (blue).

IGFBP-4 stainning of Paraffin-embedded tissue sections of human placenta (chorionic villi). Tissue was stained with  HRP-AEC Cell and Tissue Staining Kit (red) and Haematoxylin (blue).

IGFBP-4 stainning of Paraffin-embedded tissue sections of human placenta (chorionic villi). Tissue was stained with HRP-AEC Cell and Tissue Staining Kit (red) and Haematoxylin (blue).