Product Details
Catalog Number: GT15169
Applications: IHC, E, FC
Type: Sheep IgG
Immunogen: Purified, NS0-derived, recombinant mouse Repulsive Guidance Molecule A (rmRGM-A).
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse
Downloads: Datasheet (pdf)
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100 ug$365.00Add to Cart

The Repulsive Guidance Molecule (RGM) family of proteins function as BMP co-receptors. It is hypothesized that RGM family members increase the sensitivity of cells in which they are expressed to BMP stimulation, thereby allowing these cells to respond earlier or more robustly to a low level of BMP ligand.  RGM-A and RGM-B are expressed in a complementary manner in the central nervous system; whilst RGM-A mediates repulsive axonal guidance and neural tube closure,

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