Product Details
Catalog Number: GT15189
Applications: ICC, WB, E
Type: Goat IgG
Dilutions: IHC 5-15ug/mL; WB 1-2 ug/mL; E 0.5 -1.0 ug/mL
Immunogen: Purified, E. coli-derived, recombinant human tumor protein 63 (rhTP63; aa 1 - 300; Accession # NP_003713).
Storage: Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

This polyclonal anti-TP63 is predicted to recognize all isoforms of TP63, including TAp63, DeltaNp63, TP63α, β, γ, and δ. TP63, also named p63, TP73L, p51, p40 or KET, was originally identified as a p53 family member. It is highly expressed in embryonic ectoderm and in the nuclei of basal regenerative cells of many epithelial tissues in the adult including skin, breast myoepithelium, oral epithelium, prostate and urothelia. The expression of various TP63 isoforms has been suggested to play a role in development, epithelial cell maintenance and tumorigenesis.1 - 3

1. Courtois, S.  et al., 2004, Oncogene 23(3):631 - 638.
2. Koster, M.I. and D.R. Roop, 2004, J. Dermatol. Sci.  34(1):3 - 9.
3. Vincek, V.  et al., 2003, Anticancer Res. 23(5A):3945 - 3948.
Images
TP63 staining in human SSC-25 cells using. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody.

TP63 staining in human SSC-25 cells using. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody.

TP63 staining in human SSC-25 cells using. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody.

TP63 staining in human SSC-25 cells using. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody.