Product Details
Catalog Number: GT15191
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: Purified, NS0-derived, recombinant mouse Chordin (rmChordin) (aa 27 - 948).
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Rat
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$365.00Add to Cart

Chordin is an extracellular antagonist of BMP signaling which is thought to readily diffuse in tissues, thus forming gradients of BMP inhibition that result in reciprocal gradients of BMP signaling thus impacting cell fate determination along the embryonic dorsoventral axis.

This antibody will block > 95% of the binding of 100 ng/mL of rhBMP-4 to immobilized rmChordin. (100 μL of 5 g/mL was coated in each well) in a functional ELISA. 50% inhibition occurs at an antibody concentration of approximately 3 - 12 μg/mL.

Images
Chordin staining of cryostat tissue sections of mouse liver. Tissues were stained using Goat (red-brown) and counterstained with hematoxylin (blue).

Chordin staining of cryostat tissue sections of mouse liver. Tissues were stained using Goat (red-brown) and counterstained with hematoxylin (blue).

Chordin staining of cryostat tissue sections of mouse liver. Tissues were stained using Goat (red-brown) and counterstained with hematoxylin (blue).

Chordin staining of cryostat tissue sections of mouse liver. Tissues were stained using Goat (red-brown) and counterstained with hematoxylin (blue).