Product Details
Catalog Number: GT15218
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: E. coli-derived rhSOX10 (aa 1 - 118).
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 6663
UniProt: P56693
Downloads: Datasheet (pdf)
Product Sizes
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100 ug.$365.00Add to Cart

SOX10 is a member of the SRY-related HMG-box family of transcription factors. It is required for the terminal differentiation of oligodendrocytes and myelination. In the peripheral nervous system, SOX10 maintains pluripotency of neural crest stem cells and suppresses neuronal differentiation.

The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

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