Product Details
Catalog Number: GT19003
Applications: WB
Type: Goat IgG
Immunogen: Whole RSV virions (subgroup A-Long strain) were used as an immunogen. Detects G, F, N and M2 proteins of RSV.
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$295.00Add to Cart

Malondialdehyde (MDA) is a natural product formed in all mammalian cells either as a product of lipid peroxidation, or as a by-product of prostaglandin and thromboxane biosynthesis. Although MDA can be broken down by aldehyde dehydrogenases, its production is accelerated by oxidative stress and when its concentrations reach critical levels, it may escape this detoxification process. It is highly reactive and known to bind covalently with primary amino groups of proteins, phospholipids, or DNA, but has no known physiological function. This covalence modification of cellular molecules may cause structural modifications, which results in dysfunction or inactivation. MDA is toxic and has been implicated in aging, mutagenesis, carcinogenesis, radiation damage and a number of other pathological processes.

MDA is known to increase in tissue and plasma samples with age. It is known to bind to low density lipoprotein resulting in the recognition of the MDA-modified LDL by scavenger receptors on macrophages. It has also been shown to be present in renal glomerular lesions in diabetics, implicating oxidative stress as being involved in the pathogenesis of diabetic nephopathy. MDA has been shown to be increased in the brains of aged individuals and further increased in Alzheimer brains.

Image: Western blot of aged control and Alzheimer's brain homogenates using a 1:3,000 dilution of malondialdehyde antibody.

Product Reviews
Related Products
NameCatalog #
p11 (Calpactin I Light Chain / Annexin II)CH14101
BDNFCH15000
MAP2 (Microtubule assoc. protein 2)CH22103
Neurofilament NF-HCH22104
Neurofilament NF-LCH22105
Casein Kinase 1 alphaCH22109
Pin-1CH22110
PeripherinCH22111
Tau /MAPT+CH22113
Tyrosine HydroxylaseCH23006
Po (P-Zero)CH23009
PeripherinCH23016
TauCH23018
Abeta-N (beta amyloid-N-terminus)CH23020
Prion Protein/CD230CH23027
APP Peptide #3CH23028
APP Peptide #4CH23029
APP Peptide #5CH23030
ACE/CD143FC15000
RetGT15002
GDNF Receptor Alpha 1GT15004
GDNF Receptor Alpha 1 BiotinylatedGT15004B
GDNF Receptor Alpha 2GT15005
GDNF Receptor Alpha 2 BiotinylatedGT15005B
GDNFGT15007
GDNF BiotinylatedGT15007B
Presenilin 1GT15027
RAGEGT15030
Cathepsin DGT15042
Parkin-2GT15043
Caspase-3GT15044
Caspase-9GT15045
Cathepsin B (Human)GT15046
Cathepsin B (Mouse)GT15047
Cathepsin L (Human)GT15048
Cathepsin L (Mouse)GT15049
Macrophage Inflammatory Protein 1alpha (MIP-1a)/CCL3GT15070
Macrophage Inflammatory Protein 1beta (MIP-1beta)/CCL4GT15071
ADAM10 (Human)GT15078
ADAM10 (Mouse)GT15079
GDNF Receptor Alpha 4GT15083
Kallikrein 6/KLK6/NeurosinGT15097
IL-1 alpha/IL-F1GT15101
IL-1 beta (Mouse)GT15102
IL-6 (Rat)GT15106
GDNF Receptor Alpha 1GT15108
IL-1 R1/CD121aGT15109
alpha-SynucleinGT15112
Notch2GT15124
BACE-1GT15136
ACE/CD143GT15145
CXCL8/IL-8GT15156
S100BGT15160
BMP-3b/GDF-10GT15166
Jagged1GT15171
Insulysin/IDEGT15174
GDF-3GT15176
GDF-5GT15177
Bcl-2GT15194
Bcl-wGT15196
Cathepsin OGT15197
Cathepsin SGT15198
Cathepsin VGT15199
FAS Ligand (CD95L)GT15226
TLR4/CD284GT15235
VAMP-1GT15236
Dinitrophenol (DNP)GT19002
4-Hydroxynonenal (HNE)GT19004
Alsin/ALS2GT41001
Dynactin 1GT41007
LaforinGT41023
Neurogranin precursorGT41024
TRIM2GT41028
ABCA1MO13101
FAS (CD95)MO15010
Neprilysin/CD10MO15015
RAGEMO15029
Kallikrein 8/KLK8/NeuropsinMO15032
Ubiquitin+1MO15045
alpha SynucleinMO15053
BACE-1MO15066
CXCR1/IL-8 RAMO15072
CXCR2/IL-8 RBMO15073
CCR5MO15077
Omi/HtrA2MO15078
Insulysin/IDEMO15081
Serpin A3MO15082
PersephinMO15086
GDNF Receptor Alpha 1MO15093
Cathepsin FMO15096
DOPA decarboxylaseMO15100
Somatostatin Receptor-2-SSTR2MO15109
BDNFMO15115
SOD2MO15122
UbiquitinMO18001
Tau (Tau 46)MO18002
CD45MO18005
CREBMO18006
SynaptophysinMO20000
Tyrosine HydroxylaseMO20001
Beta AmyloidMO20004
APP 228MO20015
CalbindinMO20016
Cathepsin GMO20021
Neurofilament NF-HMO22103
Neurofilament NF-LMO22104
PeripherinMO22106
PGP9.5/UCHL1MO22109
alpha SynucleinMO22111
alpha SynucleinMO22112
Doublecortin/DCXMO22113
TAF15MO22114
Tar DNA Binding Protein 43 (TDP43)MO22117
Neurofilament NF-HMO22120
HSP27/HSBP1MO22123
Lamin A/CMO22124
14-3-3 etaMO22126
Ubiquilin 2MO22131
Visinin-like protein 1/VSNL1MO22132
Beta AmyloidMO22142
Muscleblind-like ProteinMO22147
DJ1/Park7MO22148
Phospho-MeCP2MO22150
UbiquitinMO22152
Tyrosine HydroxylaseMO22941
PMP22MO25033
GAPDHMO25038
PGP9.5/UCHL1MO25040
NMDA NR1 PanMO25041
ApoEMO25042
SMG-1MO30003
TRPC4MO50009
TRPC5MO50010
Glycine ReceptorRA15025
Ubiquitin+1RA15043
Caspase-3, activeRA15046
Caspase-10/b-Flice 2RA15047
Caspase-12RA15048
APPRA18003
Presenilin 2RA18004
CaMKIIRA18006
phospho-CREB (Ser133)RA18008
phospho-NMDA Receptor 1 (Ser890)RA18011
Phospho-NMDA Receptor 1 (Ser896)RA18012
ParkinRA18014
DARPP-32RA18015
phospho-DARPP-32 (Thr34)RA18016
phosphoDARPP-32 (Thr75)RA18017
Presenilin 1RA18020
alpha-SynucleinRA18021
phospho-Tyrosine Hydroxylase (Ser40)RA18026
HSP60 (D307)RA18029
HSP60 (D85)RA18030
HumaninRA19000
RattinRA19005
PARK7/DJ-1RA19006
CLAC-P (NC2-1 region)RA19007
CLAC-P (NC2-2 region)RA19008
Huntingtin-associated protein40 (HAP40)RA19010
PTEN-induced kinase/PINK1RA19013
SurvivinRA19022
WWOXRA19025
Nurr1RA19067
Notch1RA19069
Notch3RA19070
Neurofilament NF-LRA22104
PeripherinRA22109
Neurofilament NF-H, phosphate independentRA22112
Neurofilament NF-H, phosphylatedRA22116
SecretagoginRA22122
Dopamine beta-HydroxylaseRA24600
Somatostatin Receptor-1-SSTR1RA25004
Somatostatin Receptor-2-SSTR2RA25005
Abeta 40 (beta amyloid 1-40)RA25009
PTGDSRA25023
EGR2RA25024
Spectrin Beta IIIRA25025
FE65RA25029
NMDA Receptor 1, N1RA25036
NMDA Receptor 2ARA25037
BACE-2RA25043
CDR2RA25048
Ogg1RA25054
Ogg1, BiotinylatedRA25054B
Ogg1, HRP ConjugatedRA25054H
Ceramide KinaseRA25060
Glutamine SynthetaseRA25062
NMDA Receptor 2BRA25063
DOPA decarboxylaseRA25065
Macrophage Scavenger Receptor I/CD204RA25074
mTORRA25087
Mitofusion 2/MFN2RA26001
BADRA30007
BAXRA30008
PARK2 Co-regulated/PACRGRA30023
HSPA9B (mitochondrial Hsp70)RA30024
FAS Ligand (CD95L)RA30043
Synaptosomal Associated Protein 25/SNAP25RA30045
NeurotrypsinRA30051
Tyrosine HydroxylaseSO25000
Images