Chemokine receptors are seven-transmembrane domain G-protein coupled receptors that mediate the biological activities of chemokines. Most of these receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. They are named according to the chemokine subfamily they bind. There are currently eleven CC-specific receptors designated CCR1 to CCR11.
This receptor has been shown to be important for B lineage maturation and antigen driven B cell differentiation, and it may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses.
CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.
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Name Catalog # Size CCR1/CD191 MO15088 100 ug CCR5 MO15077 100 ug CXCR1/IL-8 RA MO15072 100 ug CXCR1/IL-8 RA MO15072 500 ug CXCR1/IL-8 RA-Fluorescein Labeled FC15001 100 Tests CXCR2/IL-8 RB MO15073 100 ug CXCR2/IL-8 RB MO15084 100 ug CXCR2/IL-8 RB-Fluorescein Labeled FC15002 100 Tests CXCR4 MO15022 100 ug CXCR4-Phycoerythrin Labeled FC15004 100 Tests IL-1 R1/CD121a GT15109 100 ug IL-10 MO15147 100 ug IL-10 R alpha GT15185 100 ug IL-2 R alpha/CD35 MO15070 100 ug