Product Details
Catalog Number: MO15106
Applications: WB, IHC, E, FC
Type: Mouse IgG
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, CHO cell-derived, recombinant Transforming Growth Factor beta 1 (TGF-b1) and latent TGF-b1.
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat, Primate
Downloads: Datasheet (pdf)
Product Sizes
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500 ug$325.00Add to Cart

Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts.

Image: Flow Cytometry PC-3 Cells (filled histogram) followed APC-conjugated anti-mouse antibody.

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