Neuromics loves when our customers use our products in their own research. In this case, our p75/NGF Receptor Goat IgG Antibody (GT15057) was used when exploring the receptor's importance in mice. They find that the p75 Receptor regulates behavioral response to food scarcity during the day, but not during night.
Check out the full publication here.
Image: p75NTR is expressed in AgRP neurons and is necessary for the arcuate hypothalamus response to fasting. Representative images of immunofluorescent staining for p75NTR (GT15057) in an Npy-GFP expressing reporter mouse. Courtesy of Brandon Podyma, et al. (2020). The p75 Neurotrophin Receptor in AgRP Neurons is Necessary for Homeostatic Feeding and Food Anticipation. eLife, 9:e52623. doi: 10.7554/eLife.52623.
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This publication uses our GFAP (MO15052) antibody in research on Zika Virus, finding that the virus affect astrocytes by causing ROS imbalance, mitochondrial defects, and DNA breakage. You can learn more here.
Image: Astrogliosis induced by ZIKV infection. Immunofuorescence images of MOCK-, ZIKV-infected iPSC-derived astrocytes and TNF-α condition as positive control. DAPI (blue) and GFAP (red). Scale bar: 50 μm. Pítia Flores Ledur, et al. (2020). Zika Virus Infection Leads to Mitochondrial Failure, Oxidative Stress and DNA Damage in Human iPSC-Derived Astrocytes. Scientific Reports, 10:1218. doi: 10.1038/s41598-020-57914-x
In another publication, doing diabetes pain research with our P2X3 (RA10109) antibody, they find that B vitamins can inhibit expression of P2X3 and TRPV1 in dorsal root ganglion neurons in rats. Click here to explore the full publication.