Product Details
Catalog Number: RA25044
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: Detects endogenous levels of FOXD3 protein.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$365.00Add to Cart

Embryonic stem cells require the forkhead transcriptional regulator FoxD3 for survival. Following gastrulation, FoxD3 generally gets downregulated, except in the neural crest. A variety of growth factors induce FoxD3 expression, including FGF8 and SNAIL, maintaining the effected cells in an undifferentiated state. Thus defects in FoxD3 induction may cause premature differentiation and/or migration-asociated birth defects.

Image: Western blot analysis of FoxD3 (R233) antibody in extracts from HUVEC cells.