Product Details
Catalog Number: RA30046
Applications: IHC
Type: Rabbit IgG
Immunogen: KLH conjugated synthetic peptide- N-terminal extracellular domain of humanmGluR6.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
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50 ug$435.00Add to Cart

Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

Image: mGluR6 staining of Human eye ganglion cells (Formalin-Fixed Paraffin-Embedded)

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