Membrane-Based Antibody Arrays (C-Series) are tools for screening and comparing expression levels of many cytokines, growth factors, proteases, soluble receptors, and other proteins in a wide variety of sample types.

The C-Series Arrays utilize the sandwich immunoassay principle, wherein a panel of capture antibodies is printed on a nitrocellulose membrane solid support (usualy 2.5 cm x 3 cm). The array membranes are processed similarly to a Western blot (chemiluminescent readout). Signals are then visualized on x-ray film or a digital image, allowing densitometry data collection and calculation of fold-changes for each detected protein. The entire procedure can be completed in 1 day, and is simple enough to permit even the novice researcher to successfully collect data with very few pitfalls and little or no optimization.

Many biological processes such as apoptosis, inflammation, angiogenesis, immune response and migration often accompany changes of cytokine expression levels. Because of the extensive cross-talk between cytokines, a complete analysis of biological responses and functions must be obtained through multiplex assays. The C-Series Antibody Arrays allow a much broader view of protein activity than can be obtained with single-target ELISAs and Western blots. Moreover, antibody array screening improves the chances for discovering key factors, disease mechanisms or biomarkers related to cytokine signaling.

Identification of cytokines in VF conditioned medium. A cytokine antibodies array (RayBiotech, Norcross, GA, Cat. No.AAM-CYT-3-4) identifies the presence of chemoattractant and inflammation peptides including RANTES, eotaxin, eotaxin-2, IL-4, and IL-1α. Experiments were performed according to manufacturers’ protocols. Supporting information. Coherent Anti-Stokes Raman Scattering Imaging of Lipids inCancer Metastasis. Dr. Ji-Xin Cheng et al. Purdue Cancer Center.
  • RayBio® C-Series Human Apoptosis Arrays

    Apoptosis Antibody Arrays Designed for the Simultaneous Detection of the Relative Levels of 43 Apoptosis Related Markers

    Name Catalog # Type Species Applications Size Price
    C-Series Apoptois Array 1-8 AAH-APO-1-8 Membrane-Based Array Human E 43 Apoptosis Markers-8 Sample Kit $909.00
    C-Series Apoptosis Array 1-2 AAH-APO-1-2 Membrane-Based Array Human E 43 Apoptosis Markers-2 Sample Kit $325.00
    C-Series Apoptosis Array 1-4 AAH-APO-1-4 Membrane-Based Array Human E 43 Apoptosis Markers-4 Sample Kit $489.00
  • RayBio® C-Series Human Growth Factor Arrays

    Growth Factor Antibody Arrays Designed for Analyzing Proteins that Stimulate Cellular Growth, Proliferation and Differentiation

    Name Catalog # Type Species Applications Size Price
    C-Series Growth Factor Array 1-4 AAH-GF-1-4 Membrane-Based Array Human E 41 Growth Factors-4 Sample Kit $489.00
    C-Series Growth Factor Array 1-8 AAH-GF-1-8 Membrane-Based Array Human E 41 Growth Factors-8 Sample Kit $919.00
  • RayBio® C-Series Mouse Arrays

    Cytokine Antibody Arrays Designed for Immune/Infllammatory Response, Autoimmune/Degenerative Disease Stem Cell & Cancer Research

    Name Catalog # Type Species Applications Size Price
    C-Series 1000 Mouse Cytokine Array-2 AAM-CYT-1000-2 Membrane-Based Array Mouse E 96 Cytokines-2 Sample Kit $585.00
    C-Series Cytokine Array C1-2 AAM-CYT-1-2 Membrane-Based Array Mouse E 22 Cytokines-2 Sample Kit $319.00
    C-Series Cytokine Array C1-4 AAM-CYT-1-4 Membrane-Based Array Mouse E 22 Cytokines-4 Sample Kit $499.00
    C-Series Cytokine Array C1-8 AAM-CYT-1-8 Membrane-Based Array Mouse E 22 Cytokines-8 Sample Kit $769.00
    C-Series Infammatory Response Array C1-4 AAM-INF-1-4 Membrane-Based Array Mouse E 40 Cytokines-4 Sample Kit $489.00
    C-Series Infammatory Response Array C1-8 AAM-INF-1-8 Membrane-Based Array Mouse E 40 Cytokines-8 Sample Kit $929.00
  • RayBio® C-Series Analysis Software

    The software supports antibody/protein array kit by offering Excel-based analysis software tools for the automatic computation of the extracted numerical data obtained from the array image. Features include sorting, averaging, background subtraction, positive control normalization, and histogram graphing for easy visual comparison. The analysis tools combine the familiarity of Excel with our innovative antibody/protein array technology to create a program that even the most novice researcher can easily use.

    Name Catalog # Type Species Applications Size Price
    C-Series 1000 Analyzer Software S02-AAH-CYT-1000 Software Human SE CD $169.00
    C-Series Mouse Inflammation Array Analysis Software S02-AAM-INF-1 Software Human SE CD $169.00
    Growth Factor Arrays-Analysis Software S02-AAH-GF-1 Software Software $119.00
  • RayBio® C-Series Human Angiogenesis Arrays

    Angiogenesis Antibody Arrays Designed for For Simultaneous Detection of the Relative Levels of up to 43 Angiogensis Related Proteins

    Name Catalog # Type Species Applications Size Price
    C-Series Angiogensis Array 1-4 AAH-ANG-1-4 Membrane-Based Array Human E 20 Angiogenic Factors-4 Sample Kit $489.00
    C-Series Angiogensis Array 1-8 AAH-ANG-1-8 Membrane-Based Array Human E 20 Angiogenic Factors-8 Sample Kit $729.00
  • RayBio® C-Series Human Cytokine Arrays

    Cytokine Antibody Arrays Designed for Immune/Inflammatory Response, Autoimmune Disease Stem Cell & Cancer Research

    Name Catalog # Type Species Applications Size Price
    C-Series 1000 Human Cytokine Array-2 AAH-CYT-1000-2 Membrane-Based Array Human E 120 Cytokines-2 Sample Kit $585.00
    C-Series 1000 Human Cytokine Array-4 AAH-CYT-1000-4 Membrane-Based Array Human E 120 Cytokines-4 Sample Kit $1,115.00
    C-Series 1000 Human Cytokine Array-8 AAH-CYT-1000-8 Membrane-Based Array Human E 120 Cytokines-8 Sample Kit $2,099.00
    C-Series Human Cytokine Array 1-2 AAH-CYT-1-2 Membrane-Based Array Human E 23 Cytokines-2 Sample Kit $389.00
    C-Series Human Cytokine Array 1-4 AAH-CYT-1-4 Membrane-Based Array Human E 23 Cytokines-4 Sample Kit $599.00
    C-Series Human Cytokine Array 1-8 AAH-CYT-1-8 Membrane-Based Array Human E 23 Cytokines-8 Sample Kit $1,139.00
    C-Series Human Cytokine Array 3-2 AAH-CYT-3-2 Membrane-Based Array Human E 42 Cytokines-2 Sample Kit $495.00
    C-Series Human Cytokine Array 3-4 AAH-CYT-3-4 Membrane-Based Array Human E 42 Cytokines-4 Sample Kit $495.00
    C-Series Human Cytokine Array 3-8 AAH-CYT-3-8 Membrane-Based Array Human E 42 Cytokines-8 Sample Kit $899.00
    C-Series Human Cytokine Array 5-2 AAH-CYT-5-2 Membrane-Based Array Human E 80 Cytokines-2 Sample Kit $415.00
    C-Series Human Cytokine Array 5-4 AAH-CYT-5-4 Membrane-Based Array Human E 80 Cytokines-4 Sample Kit $485.00
    C-Series Human Cytokine Array 5-8 AAH-CYT-5-8 Membrane-Based Array Human E 80 Cytokines-8 Sample Kit $1,099.00
  • RayBio® C-Series Human Inflammatory Response Arrays

    Cytokine Antibody Arrays Designed for Immune/Inflammatory Response, Autoimmune/Degenerative Disease Stem Cell & Cancer Research

    Name Catalog # Type Species Applications Size Price
    C-Series Infammatory Response Array 2-4 AAH-INF-2-4 Membrane-Based Array Human E 20 Cytokines-4 Sample Kit $489.00
    C-Series Infammatory Response Array 2-8 AAH-INF-2-8 Membrane-Based Array Human E 20 Cytokines-8 Sample Kit $729.00
    C-Series Infammatory Response Array 3-4 AAH-INF-3-4 Membrane-Based Array Human E 40 Cytokines-4 Sample Kit $489.00
    C-Series Infammatory Response Array 3-8 AAH-INF-3-8 Membrane-Based Array Human E 40 Cytokines-8 Sample Kit $909.00