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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| GT15055 | 100 ug | $345.00 | Buy Now | Add to Cart |
Type: Goat IgG
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images; ; HPLC=High Performance Liquid Chromatography; FPLC=Fast Protein Liquid Chromatography
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
Immunogen: Recombinant human Contactin-1
Description/Data:
Contactins mediate cell surface interactions during the development of the nervous system. Contactin 1 plays a role in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signalling between axons and myelinating glial cells. Contactin 1 also acts as an activating ligand for Notch1, leading to generation of oligodendrocytes. Its interaction with TNR induces neuronal repulsion and an inhibition of neural outgrowth. Contactin 1 shares the L2/HNK carbohydrate epitope with L1, N-CAM, MAG and other cell adhesion molecules from nervous tissue.