Neurodegenerative Disease

This category lists our key antibodies designed for Neurodegenerative Disease Researchers. This includes Alzheimer's, Parkinson's, Hunington's, ALS, Multiple Sclerosis and others. 

Image: Mixed neuron/glia cultures from newborn rat brain stained with peripherin (green) and phosphorylated NF-H (red). A class of large neurons, like the one in the middle of this image, contain peripherin, while the majority of neurons and their processes contain NF-H and not peripherin. Interestingly, the periperin positive cells often contain a cytoplasmic inclusion next to the nucleus which stains for both peripherin and NF-H, and so appears golden in this kind of image. The blue channel reveals the localization of DNA. Inset: Western blot of whole rat brain stem homogenate stained with Peripherin at  a dilution of 1:20,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~57kDa corresponds to Peripherin. A lower band at ~48kDa is derived from the Peripherin molecule.