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GT15004100 ug$365.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: ICC; IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ;
Species Reactivity: H; M; R
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
 
Immunogen: Recombinant rat GDNF soluble receptor alpha 1 extracellular domain.
 
Description/Data:
Picture

GDNF, Neurturin, Artemin, and Persephin are distant members of the TGF-beta superfamily that function as neurotrophic factors. Their bioactivities are mediated by a receptor complex composed of the non-ligand-binding signaling subunit (c-Ret receptor tyrosine kinase) and one of four ligand binding subunits designated GFR alpha-1 through 4, which are cysteine-rich glycosyl-phosphatidylinositol (GPI)-linked cell surface proteins.

GFRA1: Customer Publications

Picture[3]

Images: Ret and GFRA1 are co-expressed in germ cells early in spermatogenesis At P7 RET and GFRA1 co-localize in the same germ cells (yellow membrane staining). Scale bar: 25 μm. DOI:10.1095/biolreprod.105.047365.

Picture[2]

Image: GDNF R1 Alpha staining of mouse sciatic nerve cross section. Tissue stained with GDNF R1 Alpha labeled with Cy3 (red); the antibody Laminin with 488 (green) and counterstained DAPI (Blue).