|Catalog Number||Size||Price (USD)||Shopping Cart|
|GP10108||100 ul||$395.00||Buy Now | Add to Cart|
|P10108||100 ug Blocking Peptide||$95.00||Buy Now | Add to Cart|
P2X3 is a subunit in the family of ion channels activated by extracellular ATP. It was cloned from rat dorsal root ganglia. P2X3 has two putative transmembrane domains with intracellular N- and C-termini. It can form homomeric channels and heteromeric channels with other members of the family. P2X3 is expressed in nociceptive sensory neurons.
Image: P2X3 staining in rat DRG
Image: Non-petidergic fibers expressing P2X3 receptor for ATP are present in lamina II of the contralateral dorsal horn (arrows). The P2X3-positive fibers are eliminated from the rat dorsal horn ipsilateral to the rhizotomy (arrow heads). Spinal cord segment C6. Scale bar 400 um. P2X3 antibody dilution 1:25,000. Biomédica vol.24 no.2