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RA25071100 ul$315.00Buy Now | Add to Cart
 
Type: Rabbit IgG
 
Applications: FC; ICC; IF; IHC
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: Synthetic peptide from 62 base pair region of the human Ki-67 antigen.
 
Description/Data:
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GPR49 is an orphaned member of the glycoprotein hormone receptor subfamily. It is thought to play an important role in growth and differentiation of embyronic tissue. It is highly expressed in the brain, spinal cord, placenta, and skeletal muscle. GPR49 is up-regulated in several cancers.

It is also thought to be a target gene activated by Wnt-signaling.

 

Image: Immunohistochemical analysis of human small intestine using GPR49

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Image: GPR49 staining of HeLa cells  (Green) detected with DyLight Fluor 488 conjugated anti-rabbit IgG secondary antibody. Nuclei are counterstained with Hoechst 33258 (Blue).

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Images: GPR49 FACS staining of NTERA-2 cells using at a 1:50 dilution detected using Dylight-488 conjugated goat anti-rabbit IgG secondary