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GT15233100 ug$365.00Buy Now | Add to Cart
 
Type: Goat IgG
 
Applications: E; FC; IHC; WB
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Affinity Purified - liquid
 
Immunogen: Purified, NS0-derived, recombinant human CUB Domain Containing Protein 1 isoform 1 (rhCDCP1) extracellular domain.
 
Description/Data:
Picture

CDCP1 (Cub Domain-containing Protein 1), also known as SIMA135 or CD318 is a transmembrane protein that is highly expressed in skeletal muscle and colon. CDCP1 expression has been observed in metastatic colon and breast cancers.

Exclusive expression of CDCP1 in hematopoietic, mesenchymal, and neural stem/progenitor cells suggests that it can be a useful marker for these cell types.

Image: CDCP1 staining of immersion fixed paraffin-embedded sections of human colon cancer tissue at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP (brown) and counterstained with hematoxylin (blue). Specific labeling was localized to the apices of colonic villi.