|Catalog Number||Size||Price (USD)||Shopping Cart|
|RA25095||100 ul||$295.00||Buy Now | Add to Cart|
|RA25095H||50 ul @ 1 mg/ml||$315.00||Buy Now | Add to Cart|
|P25091||50 ug Blocking Peptide||$95.00||Buy Now | Add to Cart|
JARID2 or the Jumonji protein is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. It is essential for embryogenesis, including neural tube formation. It plays a key role in differentiation of embryonic stem cells and normal development. Defects in JARID2, characterized by PRC1 and PRC2 mutants, show a severely compromised capacity for successful differentiation towards neural or mesodermal fates
Images: JARID2 staining of HeLa cells using a DyLight 488 conjugated secondary antibody.
JARID2 is an excellent marker for studying differentiation patterns in induced pluripotent stem cells (iPSCs) and embyonic stem cells (eSCs).
Images: Western blot detection of JARID2 protein in E16 mouse brain lysates.